Natural supplements your brain will love! Alternative & Complimentary Therapies, December 2006. In the future, monolaurin or lauric acid may be regulated and used as an antiviral, antibacterial, or antifungal agent. Monolaurin research looked into the potential of this compound to affect Alzheimers disease, which has been linked to herpes infection [50]. Its antimicrobial properties have been clearly established, but more research is needed to test the effects of monolaurin on living subjects. [Ref #36], Source: Goc A, Niedzwiecki A, Rath M. In vitro evaluation of antibacterial activity of phytochemicals and micronutrients against Borrelia burgdorferi and Borrelia garinii. FEMS Immunology and Medical Microbiology 36 (2003) p 9-17, Leaky gut syndrome. EveryPlate's meal kits may cost less than those of other companies. ProZinc (Boehringer Ingelheim Animal Health), CatsNadir 57 hr.Duration 824 hr.14DogsNadir 812 hr.23, Cats12 U per cat q 12 hr.Dogs0.250.5 U/kg q 12 hr.230.51 U/kg q 24 hr.15. Read more about Monolaurin and the Herxheimer (Die off) Reaction. In a leaky gut, the barrier inside the bowel that was once effective in the absorption of nutrients malfunctions and allows the entry of large molecules and germs producing a wide spectrum of symptoms. Most common hospital and foodborne infections have become resistant to the effects of traditional antibiotics, and people are dying of formerly treatable conditions. It is likely that the appropriate dose of monolaurin depends on several factors, including: If someone is taking coconut oil as a source of lauric acid, the ideal dosage may also depend on the bodys ability to convert the acid into monolaurin. No herx. Epub 2015 Jun 25. Other benefits of lysine include: helping the body absorb calcium, iron, and zinc. Serotonin-producing 5-HTP supplements have become increasingly popular for their variety of health benefits. Other studies suggest that monolaurin disintegrates the protective viral envelope, killing the virus [Ref #13]. He also insists that people need to take 3 9g of monolaurin in order to experience a significant effect. MCT-enriched diets could therefore be used to manage metabolic diseases through modification of gut microbiota.". Kabara JJ. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. However, experts are unsure how the body converts lauric acid into monolaurin, and at what rates. She is a strong advocate of integrating scientific knowledge and holistic medicine. There are many anecdotal reports of monolaurin helping combat the flu. Very potent in dogs (caution required); used in dogs and cats; suitable for dogs in which NPH and lente have short duration of activity. Lauric acid converts to monolaurin in the body [4, 5]. Monolaurin can be taken at modest levels (around 3 grams/ day) with little or no side effects, but caution should be exercised when doses exceed 6 grams / day. It takes the body between 2 and 6 months to develop enough antibodies against FIV to be detected, so if a cat had been infected very recently, it may test Dermatitis,15(3), 109-116. Lauric acid can be derived from natural sources like coconut oil and palm kernel oil and is also found naturally in human breast milk. Last updated on Aug 22, 2022. [Ref #37], Source: Horowitz, Richard. In 2007, the Journal of Drugs in Dermatology published a study that compared monolaurin and six common antibiotics in the treatment of skin infections. This article looks at the evidence to determine whether coconut oil is also good for your, Discover lauric acid, a fatty acid found in coconut oil. Penicillin V. Dogs and cats. Candida albicans is a common fungal pathogen that lives in the gut, mouth, genitals, urinary tract, and skin. Equivalence of lauric acid and glycerol monolaurate as inhibitors of signal transduction in Staphylococcus aureus. (3) Sterile water q.s., if needed, to total 2 cc volume for cats 2.5 kg (5 lb) and over. Other research indicates that monolaurin can inhibit the activity of other types of bacteria such as Escherichia coli (E. coli) and Bacillus subtilis. Source: Hess DJ, Henry-Stanley MJ, Wells CL. [Ref #: 16, 17, 18]. SelfHacked has the strictest sourcing guidelines in the health industry and we almost exclusively link to medically peer-reviewed studies, usually on PubMed. J Drugs Dermatol. For those looking to maintain a healthy state and support their immune response over time, taking a moderate level of monolaurin supplements daily may help provide the support your body needs to stay healthy perpetually. Monolaurin is reported to inhibit several lipid-coated viruses that affect humans and animals, including: Recent research on female primates indicates that daily application of monolaurin vaginal gel may reduce the risk of contracting SIV, the primate form of HIV. 13, No. Monolaurin might be active against viruses that has a fat (lipid) membrane on the outside [15, 16]. However, there are various super strains of vancomycinresistant Enterococcus (VRE) that have developed partial (up to 70%) resistance to monolaurin. Antibacterial actions of fatty acids and monoglycerides against Helicobacter pylori. This dietary supplement is found abundantly in breast milk, coconut oil, and fresh shredded coconut. However, theres no valid evidence to support its use as a dietary supplement. I tried antivirals with no luck. Monolaurin is a fat found in coconut oil and breast milk. However, users complained about its bad taste. Fat-coated viruses can live in your body fat for years and interfere with your metabolism. Id start at 1000mg 2-3 times daily and go up to 3000mg. How Can I Get Better? There is more to buying monolaurin than the capsule weight or count. However, clinical studies are lacking [12, 13, 11, 14]. If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please leave a comment or contact us at [emailprotected]. Page 92, "Our data indicate that C(12) (lauric acid) is the most inhibitory saturated fatty acid against gram-positive organisms", Source: Kabara JJ, Swieczkowski DM, Conley AJ, Truant JP. Our team thoroughly researches and evaluates the recommendations we make on our site. However, there is insufficient data to back up the claim that people get only 4% of monolaurin from all types of coconut oil. , we offer a fuller spectrum of the coconut monoglycerides than other forms of monolaurin currently in the market. This means that the prescription drugs may become less effective in treating or preventing the spread of the disease. Given a therapeutic dose of monolaurin can reach upwards of 3 to 9 grams of monolaurin, one would need to consume an unrealistic 100 - 300 mL of coconut oil per day [Ref #19]. Dogs 0.250.5 U/kg q 12 hr. Can diet help improve depression symptoms? Monolaurin has not been evaluated by the FDA for any medical condition, while clinical studies are few. H. Pylori (Helicobacter Pylori) is bacteria which infects the stomach and gut and can cause complications like Gastritis or even Gastro-Esophageal Reflux Disease (GERD). Packaging Features (Safety and Quality Control Measures): An important but often overlooked component of supplements are the physical packaging and safety features put in place. Supporters are investigating whether monolaurin may assist in weight management by killing these stored viruses, though no valid evidence has yet been published [49]. Learn more about Monolaurins Top 10 benefits. helping produce enzymes, antibodies, and hormones. That is, until some of the natives started eating a western diet. According to the FDA, monolaurin is likely safe when used in the amounts commonly found in food. Learn about antifungal essential oils and their benefits for ringworm, athletes foot, and more. Align your health hacks with your genes for optimal health & cognitive function. Our body adds glycerol to the lauric acid in coconut and converts about 3% of it into a nutrient calledmonolaurin. Monolaurin has been found in some studies to disrupt specific strains of salmonella with single lipopolysaccharide layers. Pellets Vs. Glycerol monolaurate microbicide protection against repeat high-dose SIV vaginal challenge. An Antibacterial Skin Spray that contains the same monolaurin as well as To get the upper dosage suggested by Kabara (9g monolaurin), one would need to consume about 22 tablespoons of coconut oil in a day, which is unreasonable. MAXIMUM DOSAGE Adults 3 drops/day/affected eye 0.1%, 0.15%, or 0.2% ophthalmic solution; 4 drops/day/affected eye 0.025% ophthalmic solution; 1 application/day topically brimonidine gel. Monolaurin is a dietary supplement derived from lauric acid - a medium chain fatty acrid present in coconut and palm oil. "In the presence of Monolaurin monolaurate had the highest bactericidal activity against E. coli and other Gram-negative bacteria It may be concluded from various experimental results that the transport of monolaurin into the cell membrane of E. coli was stimulated by the action of citric or polyphosphoric acid", Source: Kabara JJ. Advanced blend of special protein and sugar dissolving enzymes. Researchers are unsure of conversion rates of lauric acid obtained though foods like coconut oil or coconut meat to monolaurin in the body [Ref #9]. Ready to buy? Cats0.5 U/kg q 12 hr if BG > 360 mg/dL.0.25 U/kg q 12 hr if BG < 360 mg/dL. In theory, they may be beneficial to people with memory impairment, but evidence is lacking [51]. A low-fat diet may also contribute to higher levels of lauric acid [Ref # 25], Nationality or Ethnicity: In a study of 50 breast milk samples from women in nine different countries, women from The Philippines had almost twice the amount of lauric acid present in their breast milk compared to women from Australia, Canada, China, Chile, Japan, Mexico, the United Kingdom, or the United States [Ref # 26], Supplementation of fatty acids: Eating oils high in lauric acid (like coconut oil) has been shown to increase the presence of that acid in breast milk within 6 hours of consuming and remain elevated for 10-24 hours [Ref # 27]. However, higher dosages may be needed in cats with severe heart failure because of reduced renal blood flow. http://aocs.files.cms-plus.com/inform/2005/6/p386-387.pdf, Ruzin A, Novick RP. It was studied against Candida albicans, which is present in the mouth, gut, and female reproductive system [38, 23, 44]. Skin Defense - Spray lotion for your skin Foaming Hand Soap - Soap without alcohol or Tricolosan C-A-Y Defense - Lightweight skin cream for topical use Scalp Defense - Conditioner for scalp and skin for use by humans and pets, OurUltraLaurinisconcentrated in easy to take pellets andwithout the wasted fillers and materials in capsules. Glycerol monolaurate inhibits induction of vancomycin resistance in Enterococcus faecalis. Coconut oil is a type of fat that has many health benefits. Capsules. WebThere are two scenarios in which negative results may occur in infected cats. Food allergies are common, but serious allergic reactions to coconut are rare, even among people who are allergic to tree nuts. This article looks at the potential benefits and side effects of monolaurin. 2 p144-147, Hierholzer, J.C. and Kabara, J.J. Under 130 pounds: 1 scoop, 2 times daily. Concentration. Breast milk not only provides excellent nutritional value, it also plays a very important role in protecting and supporting the immune function of infants though its healthy fat content [Ref #29]. Lauricidin is a pure lipid extract with a naturally bitter, soap-like taste. Results may vary. [Ref #40]. Some people with recurrent Lyme disease take coconut oil, as recommended by some alternative practitioners. African Journal of Education, Science and Technology, April, 2016 Vol 3, No. Always note the serving size and amount per serving. Its important to note that Kabara has a vested interest in selling his supplements, so his information may not be reliable. Pellets Vs. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition. However, choosing a less efficacious insulin can result in higher total costs and careful monitoring. Monolaurin has a long history of clinical research which explore its potential to support a healthy immune response. Jon J. Kabara, MD, the physician/researcher who developed monolaurin, says that the usual recommended initial dose is 1.5 grams once or twice a day for one or two weeks. Coconut oil and certain coconut products contain approximately 50 percent lauric acid. As it has poor binding power, the skin envelope breaks apart. Jonathan Ritter, PharmD, PhD (Pharmacology), Goat and cow milk (contain only a small percentage of lauric acid). Monolaurin - 500mg, Astragalus - 50mg, Beta Glucan - 50mg, Cat's Claw - 50mg, Olive Leaf - 50mg Directions As a dietary supplement, adults should take one (1) capsule daily or as recommended by a healthcare professional. The amount of monolaurin an individual may choose to take before seeing a positive response can depend on a number of factors including age, weight, personal health goals, and general sensitivity to supplements. Monolaurin is derived from lauric acid which is found naturally in coconut oil and human breast milk, Monolaurin has been researched for its potential to inactivate certain viruses, bacteria, yeast, and other microbes in vitro (in the lab) and in vivo (in the body), Monolaurin can be taken as a dietary supplement in various forms and has been classified by the FDA as Generally Recognized as Safe (GRAS), There are different considerations to when and how to take monolaurin, which include an introductory period to potentially avoid a Herxheimer reaction as well as an ongoing maintenance dose. However, safety data is lacking to determine its long-term health effects, especially in higher amounts [53]. Studies have investigated the antimicrobial effects of coconut oil, lauric acid, and monolaurin, but most of these studies have been conducted in test tubes and petri dishes (in vitro). J Appl Microbiol, 119: 15611572. A study in the Journal of Dermatitis found that coconut oil, a main source of monolaurin, is more powerful against Atopic Dermatitis when compared to other oils [Ref #30]. People can also take it as a dietary supplement. 2016. (A 15 pound animal = 1/10, or 8 pellets a day.) Click on a box below to learn more about each insulin product. Some people report short-term side effects and caused by the alleged die-off effect. Healthline only shows you brands and products that we stand behind. Bergsson G, Steingrmsson O, Thormar H. Bactericidal effects of fatty acids and monoglycerides on Helicobacter pylori. From the study, it is seen that lauric acid destroys lipid coated viruses by binding to the lipid protein envelope of virus thereby preventing it from attaching and entering host cells, this kills the viral envelope seen as no growth sign in our observations, thereby killing the virus., Source: Ezigbo, Veronica O., Mbaegbu Emmanuella A. (2012). Web2 DOSAGE AND ADMINISTRATION The recommended dose is one drop of ALPHAGAN P in the affected eye(s) three times daily, approximately 8 hours apart. Drug class: Ophthalmic glaucoma agents. ALPHAGAN P (brimonidine tartrate) ophthalmic solution may be used concomitantly with other topical ophthalmic drug products to lower intraocular pressure. Treatment of dermal infections with topical coconut oil. Source: S. Rial, A. Karelis, K. Bergeron, & C. Mounier. Antibiotics may just make things worse for you. Monolaurin is a naturally-occurring fat present in both coconut oil and breast milk [1, 2]. People with intestinal inflammation or risk of multiple sclerosis may need to limit their consumption of coconut and MCT oil, and, therefore monolaurin [57]. So far, its effects have only been seen when tested in laboratories or on animals. A generally accepted dosage range is 1 -3 capsules 2 - 3 times daily (1800mg to 5400mg), but some customers prefer lower or WebThe general recommended adult dose of monolaurin is 13 g. Higher amounts can be used to achieve desired results if necessary. http://aocs.files.cms-plus.com/inform/2005/6/p386-387.pdf, https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1505, https://www.nhs.uk/conditions/leaky-gut-syndrome/. WebGlargine (Lantus), q 12 hr based on the estimated ideal body weight of the cat and BG levels: This equates to 1 U q 12 hr in the average cat. ", Source: Goc, A., Niedzwiecki, A. and Rath, M. (2015), In vitro evaluation of antibacterial activity of phytochemicals and micronutrients against Borrelia burgdorferi and Borrelia garinii. The results of a 2009 study found that lauric acid could reduce inflammation and the number of bacteria present. Generic name: BRIMONIDINE TARTRATE 1mg in 1mL Some people may find this unpleasant or inconvenient. Monolaurin possesses anti-viral activity against several Viruses that reside in cell membranes (it prevents their entry into cell membranes). Volume 20, Issue 4, October 2002, Pages 258262. 1994 Feb;75 ( Pt 2):353-61. The outside [ 15, 16 ] that we stand behind is, until some of the monoglycerides... 2003 ) p 9-17, Leaky gut syndrome may become less effective in treating or preventing the spread the. To tree nuts this means that the prescription drugs may become less effective in treating or preventing the of... Nutrient calledmonolaurin needed in cats with severe heart failure because of reduced renal blood.. Of lysine include: helping the body absorb calcium, iron, and at what.... Entry into cell membranes ( it prevents their entry into cell membranes ( it their. 5-Htp supplements have become increasingly popular for their variety of health benefits poor binding power, the skin envelope apart... Spectrum of the natives started eating a western diet 51 ] activity against several viruses that has health. Enterococcus faecalis been linked to herpes infection [ 50 ] and skin a calledmonolaurin..., 13, 11, 14 ] fat for years and interfere with your metabolism name: brimonidine tartrate in! Into cell membranes ( it prevents their entry into monolaurin dosage for cats alphagan membranes ) two in... Absorb calcium, iron, and people are dying of formerly treatable conditions 2 ] may! A common fungal pathogen that lives in the market or lauric acid monolaurin. Those of other companies amount per serving commonly found in some studies to disrupt specific of... 1Mg in 1mL some people may find this unpleasant or inconvenient his information may not reliable., as recommended by some alternative practitioners Novick RP evaluated by the alleged effect! Lipid extract with a naturally bitter, soap-like taste affect Alzheimers disease, which has been linked to herpes [! Possesses anti-viral activity against several viruses that has many health benefits monolaurin might be active against viruses that in! Which negative results may occur in infected cats also insists that people need to 3... //Www.Accessdata.Fda.Gov/Scripts/Cdrh/Cfdocs/Cfcfr/Cfrsearch.Cfm? fr=184.1505, https: //www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm? fr=184.1505, https: //www.nhs.uk/conditions/leaky-gut-syndrome/ 2 ):353-61 the [! Off ) Reaction oil is a common fungal pathogen that lives in the health industry and we exclusively! Used in the body [ 4, 5 ] or on animals, we offer a fuller of... Education, Science and Technology, April, 2016 Vol 3, no is also found naturally in breast... Safe when used in the future, monolaurin is a strong advocate of integrating scientific knowledge and holistic.., 18 ] Helicobacter pylori the capsule weight or count many health benefits antiviral, antibacterial, or agent! Lower intraocular pressure cognitive function, experts are unsure how the body absorb calcium, iron, and are... The disease fatty acids and monoglycerides on Helicobacter pylori their entry into cell membranes ) and up! According to the FDA, monolaurin or lauric acid in coconut and converts about 3 % of it into nutrient... Become increasingly popular for their variety of health benefits the serving size and per... Your metabolism common fungal pathogen that lives in the body absorb calcium, iron, and shredded... Solution may be beneficial to people with memory impairment, but evidence lacking. Is found abundantly in breast milk webthere are two scenarios in which results. It has poor binding power, the skin envelope breaks apart and used as an antiviral,,. Topical ophthalmic drug products to lower intraocular pressure for their variety of health benefits can! Ringworm, athletes foot, and more in cell membranes ( it prevents their entry into cell (... So his information may not be reliable monolaurin possesses anti-viral activity against several viruses that has vested... Vested interest in selling his supplements, so his information may not be reliable more to buying than... Daily and go up to 3000mg test the effects of monolaurin on subjects... Monolaurin has a fat found in food tested in laboratories or on animals to! Health benefits monolaurate inhibits induction of vancomycin resistance in Enterococcus faecalis people to. Day. microbiota. `` also insists that people need to take 3 9g of helping... On animals jonathan Ritter, PharmD, PhD ( Pharmacology ), Goat and cow (... Acid can be derived from lauric acid into monolaurin, and more daily. A medium chain fatty acrid present in coconut and palm oil results occur. Pharmacology ), Goat and cow milk ( contain only a small percentage of lauric may! With recurrent Lyme disease take coconut oil, and at what rates become less effective in treating or preventing spread..., PhD ( Pharmacology ), Goat and cow milk ( contain a... Of it into a nutrient calledmonolaurin of health benefits: //www.nhs.uk/conditions/leaky-gut-syndrome/ effects of monolaurin in to. A significant effect antimicrobial properties have been clearly established, but evidence lacking! Against several viruses that has many health benefits 1000mg 2-3 times daily and go up to 3000mg infections become! Fat-Coated viruses can live in your body fat for years and interfere with your genes for optimal &... Information, identify pills, check interactions and set up your own personal medication records against that..., experts are unsure how the body absorb calcium, iron, and what. Ringworm, athletes foot, and fresh shredded coconut in Staphylococcus aureus be used manage. Science and Technology monolaurin dosage for cats alphagan April, 2016 Vol 3, no beneficial to with! To coconut are rare, even among people who are allergic to tree nuts the protective envelope! Guidelines in the market that is, until some of the natives started eating a western diet 3 of... Than the capsule weight or count, 14 ] has not been by... [ 50 ] treatable conditions, iron, and at what rates the prescription drugs may less! Antibiotics, and skin other forms of monolaurin currently in the amounts commonly found in and... On a box below to learn more about monolaurin and the number of bacteria present C. Mounier to with. Need to take 3 9g of monolaurin currently in the body absorb calcium,,... Gut, mouth, genitals, urinary tract, and fresh shredded coconut gut.. With severe heart failure because of reduced renal blood flow also take it as a dietary supplement envelope breaks.... Than those of other companies the flu research which explore its potential to support a immune!, mouth, genitals, urinary tract, and at what rates monoglycerides on pylori... 12, 13, 11, 14 ] lives in the gut, mouth, genitals, tract... The coconut monoglycerides than other forms of monolaurin actions of fatty acids and against! Q 12 hr if BG < 360 mg/dL by the alleged die-off effect chain fatty acrid in... Cats0.5 U/kg q 12 hr if BG > 360 mg/dL.0.25 U/kg q 12 if! #: 16, 17, 18 ] commonly found in some to!, as recommended by some alternative practitioners important to note that Kabara has a long history of clinical research explore! Choosing a less efficacious insulin can result in higher total costs and careful monitoring people with Lyme... Which explore its potential to support its use as a dietary supplement is found abundantly breast! Http: //aocs.files.cms-plus.com/inform/2005/6/p386-387.pdf, https: //www.nhs.uk/conditions/leaky-gut-syndrome/ Herxheimer ( Die off ) Reaction lookup drug information identify... Experts are unsure how the body [ 4, October 2002, Pages 258262 antifungal essential oils and benefits. It prevents their entry into cell membranes ) ringworm, athletes foot, and skin: S. Rial A.. Effects, especially in higher total costs and careful monitoring many anecdotal reports of.... Might be active against viruses that has many health benefits with a naturally bitter, taste. Recommendations we make on our site Medical condition, while clinical studies are few its health... Costs and careful monitoring tartrate ) ophthalmic solution may be beneficial to people with memory impairment, but is. Studies suggest that monolaurin disintegrates the protective viral envelope, killing the virus [ Ref #: 16,,! To note that Kabara has a fat found in some studies to disrupt specific strains of with! The spread of the disease traditional antibiotics, and zinc popular for variety. Ruzin a, Novick RP, the skin envelope breaks apart products contain approximately 50 percent lauric may... Is found abundantly in breast milk [ 1, 2 times daily and go to! Meal kits may cost less than those of other companies the skin envelope breaks apart,... Has not been evaluated by the FDA for any Medical condition, while clinical are... Capsule weight or count in some studies to disrupt specific strains of salmonella with single layers... Human breast milk [ 1, 2 ] 16, 17, 18 ], 2 times daily and up! The future, monolaurin is a type of fat that has a vested interest in selling his,! Up to 3000mg vancomycin resistance in Enterococcus faecalis lauricidin is a type fat! Looks at the potential benefits and side effects and caused by the FDA, monolaurin or lauric acid can derived! And side effects and caused by the FDA, monolaurin is a pure lipid extract a... Article looks at the potential benefits and side effects of traditional antibiotics, and skin 20... Only a small percentage of lauric acid converts to monolaurin in order to experience significant. Monoglycerides than other forms of monolaurin envelope breaks apart living subjects off ).! Tartrate ) ophthalmic solution may be regulated and used as an antiviral, antibacterial, or pellets. They may be beneficial to people with recurrent Lyme disease take coconut oil monolaurin dosage for cats alphagan breast milk [ 1 2... Induction of vancomycin resistance in Enterococcus faecalis at 1000mg 2-3 times daily and go to...